NAD + Resveratrol and aging

NAD boosters might work synergistically with supplements like resveratrol to help reinvigorate mitochondria and ward off diseases of aging.

Each of our cells has its own tiny “powerplant” called mitochondria and as we age, the fuel supply that our mitochondria need to do their job is radically reduced. The name of that “fuel” is NAD and without it, we would die in seconds.

Nicotinamide riboside increases cellular levels of NAD+. Resveratrol supports the healthy expression of longevity genes. These two are combined into an innovative nutritional supplement.

DESCRIPTION:
The combination of NR and Resveratrol helps produce NAD+, which promotes healthy DNA cell structure. This is critical for healthy aging. NAD and its precursors have likely been discussed more than any other longevity molecules, at least in the last year. We know that NAD levels decline as
we age, and this may be one of the central mechanisms behind why we age. Nicotinamide riboside (NR), a precursor of NAD, has been studied to promote longevity in many different organisms. It works by contributing to promote DNA repair, modulating immune-cell signaling, inducing energy-intensive enzymes, etc., supporting energy production, and most importantly activating sirtuins.

This product contains Resveratrol and Pterostilbene for added anti-aging support for the body. Resveratrol is called a fasting mimetic. This means that it has properties similar to calorie restriction (CR), which has been studied to increase lifespan in multiple organisms, including primates. Specifically, both resveratrol and CR up-regulate telomerase, increase expression of both SIRT1 and FOXO3, and act via other additional mechanisms. CR involves retardation of growth, reduction of body fat, delays neuroendocrine and immunologic changes, increases DNA repair capacities, enhances apoptosis, and ameliorates oxidative stress. Human studies are trying to determine if resveratrol can reverse some markers of Alzheimer’s disease, improve blood pressure, and improve cognitive performance in patients with diabetes, among other promising effects. Pterostilbene is a polyphenol found in wine and blueberries which is very
structurally similar to resveratrol. The only difference is that it is able to stay in the body much longer to exert its effect. It has been studied for effects on the hallmarks of aging, including oxidative damage, inflammation, telomere attrition and cell senescence.

Information provided for educational purposes only. No therapeutic claims are made for the products or ingredients described.

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